Fast and Specific Hybridization Using Flow-Through Microarrays on Porous Metal Oxide
نویسندگان
چکیده
منابع مشابه
Specific and nonspecific hybridization of oligonucleotide probes on microarrays.
Gene expression analysis by means of microarrays is based on the sequence-specific binding of RNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving sequences other than the intended target is problematic because it adds a chemical background to the signal, which is not related to the expression degree of the target gene. The artic...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2001
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/47.10.1931